You sirs are completely correct, at least for what concerns me. I never intend to work on a 3D engine again in my life (especially now that I like to make games for my own amusement, and I'm both the coder and the artist). There are too many parts in a 3D game assets pipeline for me to quickly prototype exactly what you describe (the resulting feeling), until I get exactly what I meant to make.
Call it nostalgia, i was born in '78 after all, call it whatever you want, but I just don't like it as much as good 2D.
Don't get me wrong, I'd never render in software these days, and only use OpenGL, since I still like to use the GPU for dynamic shadows/lighting/particle effects, but the best game art for me is and will always will be 2D.
What turns me on these days are titles like these in the works:
Heart forth Alicia
Witchmarsh
Glorious!
And if I shall ever get to sell something I made, I wouldn't do it for the money, and I'd be super happy if I hit a niche of 10k players only, that appreciates the same stuff I do.
Ingredient #1 of every good game, however humble, is LOVE. Can't make something that doesn't move me deeply, now can I?
P.S. I absolutely loved Full Throttle, and N for me was a masterpiece. I actually ported the N physics engine to Javascript with Metanet's permission. You can check it out
here (arrow keys to move).